PhD Projects for Biological Science Graduates
Please register your interest with our online feedback form if you would like us to contact you should we have any similar opportunities available at a later date.
Please indicate which scientific disciplines (Biology, Chemistry, Physics & Engineering, Mechanism-based drug discovery) you are interested in.
PLEASE NOTE - projects marked with an asterisk (*) have special eligibility requirements and stipend arrangements.
Breakthrough Breast Cancer Research Centre
Stromal fibroblasts in breast cancer
Professor Clare Isacke
Cancer Research UK Centre for Cancer Therapeutics
Genes involved in sensitivity and resistance to PI3 kinase inhibitors
Professor Paul Workman
Joint Department of Physics
Multiscale modelling of tumour evolution, diagnosis, prognosis and therapy in breast cancer
Drs Dimitra Darambara and Marketa Zvelebil
Section of Cancer Genetics
Professor Nazneen Rahman
Section of Cell and Molecular Biology
The role of lysyl oxidase in colorectal metastasis
Dr Janine Erler
Mechanism and significance of conformation-selective ligand-binding by the retinoblastoma protein
Dr Sybylle Mittnacht
Section of Gene Function and Regulation
The role of beta-catenin in prostate development and function
Dr Amanda Swain
Section of Molecular Carcinogenesis
Impact of carcinogens on causing mutational inactivation of the p53 gene in human tumours
Professor David Phillips
MicroRNAs involved in myogenesis and childhood tumours resembling skeletal muscle development
Dr Janet Shipley
Section of Structural Biology
Structural basis for PCNA regulation by monoubiquitylation
Professor Laurence Pearl
Structural studies of human tripeptidyl peptidase II
Dr Ed Morris
Characterisation of the tumour suppressor menin and its role in the MLL chromatin regulation complex
Dr Jon Wilson
Structural characterisation of MLL interactions
Dr Jon Wilson
Section of Paediatric Oncolgy
Dr Louis Chesler
Mechanism-based Drug Discovery
Histone methyltransferase Prmt1 in normal development and cancer therapeutics*
Drs Eric So and Jon Wilson
Targeted disruption of TPR-domain recruitment to the Hsp90/Hsp70 molecular chaperone systems*
Professors Paul Workman and Laurence Pearl