|
History
The
Clinical Trials and Statistics Unit was established in the
1980s at The Institute Of Cancer Research (ICR) as part
of the Section of Epidemiology.
Under Judith Blisss leadership the ICR-CTSU has developed
from a small local statistical support group into an independent
research section with a national reputation and an increasing
international perspective. The ICR-CTSU receives core funding
from Cancer Research
UK.
The
main objective of the ICR-CTSU is to design, initiate, conduct
and analyse national and international randomised clinical
trials of cancer treatment which will directly influence
routine clinical practice within the National Health Service
and worldwide.
Our trials form
an important component of the National
Cancer Research Networks portfolio of randomised trials
in breast cancer, melanoma and urological cancers.
The
ICR-CTSU also provides a randomisation service for 24 Phase
II and III trials run locally (Royal Marsden Hospital Trust
and other Trusts in the South-West London Cancer Research
Network).
During
2003 we have:
- become an NCRI accredited trials unit
-
completed accrual of over 4,000 patients,
in under 30 months, to the UK TACT trial assessing sequential
Taxotere as adjuvant chemotherapy in early breast cancer
Associated
research
Integral
Quality of Life (QOL) studies are routinely conducted as
part of ICR-CTSUs clinical trials. For three of our breast
cancer trials (ABC, START, and TACT) similar instruments
have been used, thus providing datasets that can be combined
to provide highly detailed QOL data on large numbers of
breast cancer patients (eg single measures such as separate
anxiety and depression levels can be compared and contrasted
between populations participating in different trials).
The
added value of collecting histological specimens (bloods,
tumours) within large scale randomised trials is well recognised
by ICR-CTSU and translational research forms a key component
of our collaborative research programme.
Summary
of Current Trials
For
general enquiry -
|
 |
Staff Contacts
Publications
Jobs
Highlight
of 2003
Associated
Research
Summary
of Current Trials
Summary
poster
Last Updated:
January 28, 2005
|