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Research    
Research Groups: Joint Department of Physics  

 

 
RADIOLOGICAL PHYSICS GROUP, CHELSEA
Head of Medical Physics Chelsea:
D R Dance PhD

Head of Radiological Physics Group and RPA:
S H Evans MSc

Radiation Protection and Staff Dosimetry Service

SH Evans, IA Castellano, BE Pratt, S Dhanse, L Martinez , S Chima, A Spencer, RE Doull, E McDonagh

We continue to provide an approved dosimetry service to the Royal Marsden, The Institute of Cancer Research and the Royal Brompton and Harefield NHS Trust (Brompton site). This service has now been extended to the Harefield site. We also continue to provide a calibration service for contamination monitors throughout the Trust.  Radiation protection shielding for the new PET suite and for the relocation and upgrade of the systemic iodine suite have been evaluated. Attention remains focused on the requirements of the Ionising Radiations Regulations 1999 (IRR99) and the Ionising Radiations (Medical Exposures) Regulations (IRMER). The Medical Exposures Committee and the Trust’s Radiation Protection Committee continue to oversee the implementation of the IRMER and the IRR99. During the year the group has focused on ensuring departments are fully compliant with the new regulations, particularly with the auditing requirements under the Clinical Governance framework. We also supply extremity dosimeters to Brighton NHS Trust and a hospital in Portugal. Staff are monitored mainly using film badge dosimeters. The radiographs formed when the films are exposed to radiation are visually inspected by our staff prior to densitometric evaluation of the films’ densities.  Over 15,000 dosimeters were processed and evaluated last year.

               

A member of staff measuring films                              Film badges



The following is a list of some of the main features of our dosimetry service:

  • personalised badges for positive ID of staff
  • maximum 10 day reporting of doses
  • immediate response (1 working day) to evaluation of doses to staff exposed accidentally
  • radiation protection advice on the significance of staff doses
  • results available on hard copy or electronic media
  • visual and densitometric evaluation of films
  • flexibility in response to changes in needs
  • individual and personal approach
  • doses measured down to 0.01mSv

Some of the other main functions of the Group are outlined in the following sections.


Comparison of Personal Dosemeters for the Measurement of Low Radiation Doses
TO Faleye, CL Skinner, SH Evans
Source of funding:The RoyalMarsden

The dose thresholds of personal monitoring film, thermoluminescent dosimeters (TLDs) and electronic personal dosemeters (EPDs) were measured at various photon energies. Film was found to have a dose threshold of 0.04mSv. The dose thresholds of TLDs were found to be 0.02mSv and 0.002mSv depending upon the phosphor type. Above 0.1mSv, the average deviation from the applied dose of all dosemeters was better than 15%. Below 0.1mSv, the response for film badges were unreliable. The PDs did not respond adequately to pulsed high doserates.

Diagnostic Radiology Physics Quality Assurance Service
SH Evans, IA Castellano, CL Skinner, L Martinez, K Bell, ET McDonagh
Source of funding: The Royal Marsden

We continue to supply a diagnostic radiology quality assurance service to a number of hospitals. Recent advances in X-ray equipment have expanded the scope of our work to include spiral CT scanners, advanced cardiac units and digital X-ray equipment such as computed radiography systems and digital mammography units. The sophistication of such equipment requires up-to-date knowledge of technological and clinical developments. In 2002 we commissioned a 4-slice CT scanner; an upgrade to an electron beam CT scanner; two full field digital mammography units; a simulator with a flat-panel imager; and two mobile units. We are also involved in writing technical specifications for new equipment, and evaluating the models offered prior to purchase. This information is then used to decide on the manufacturer that best meets the clinical requirements. In 2002 we prepared the technical specification for an upgrade to an electron beam CT scanner, and assessed three 16-slice CT scanners. The scope and frequency of the tests comply with the recommendations set out in IPEM report 77: "Recommended standards for the routine performance testing of diagnostic X-ray imaging systems". The Group aims to provide a very high level of service incorporating thorough measurements and good liaison with staff in the X-ray departments to explain our results and any action that needs to be taken. In addition, we follow up our recommendations and liaise with service engineers. We have recently been updating our reporting methods and have developed a range of spreadsheet templates to provide direct data entry into a notebook PC that also facilitates preliminary analysis of measurements. Patient dosimetry is performed according to national protocols where these are available, and our own protocols are developed where necessary. Particular attention is given to high-dose procedures such as examinations using fluoroscopy. Results are also compared with national and European reference levels when these are available. It is encouraging to note that our patient dose measurements are below the reference levels published by the NRPB. Such information provides objective evidence of differences in practices and equipment.

Radiation Protection Training
SH Evans, IA Castellano Smith, B Pratt, CL Skinner, E Santusova.
Source of funding : RMT, external delegates

Proper training of staff is essential for both staff and patient protection against unwanted exposure to ionising radiation. We will be running our eleventh annual Radiation Protection Training Course (RPTC) this year. It lasts one week and has gained both national and international recognition. IRMER (Ionising Radiation (Medical Exposure) Regulations 2000)) courses have been run to satisfy the legal training requirement for key staff concerned with radiation protection of the patient both for brachytherapy and unsealed source therapy.

Radiographic Techniques and Lesion Detection in Digital Mammography
DR Dance, RA Hunt, IA Castellano; in collaboration with W Huda, SUNY, Syracuse, New York. Source of funding: US Department of Defence Breast Cancer Research Program, The Royal Marsden

The Royal Marsden has X-ray equipment which can capture digital mammograms and can produce image quality to match or exceed that for conventional screen/film mammography. The equipment has exciting potential for improvement of the small cancer detection rate. We are making a combined experimental and theoretical study of how best to utilise digital mammographic systems. We aim to quantify the improvement in image quality and to identify imaging configurations (X-ray spectrum and exposure) which will produce the desired image quality at the smallest breast dose. Experimental observer studies by our USA collaborators have used the ACR phantom and an anthropomorphic phantom to study the detection of small cancers. The results have been successfully compared with the predictions of our theoretical model of the imaging system. Both approaches are being combined to find operating configurations which can reduce breast radiation dose whilst matching or improving image quality.

Patient Dose Optimisation in Computed tomography
IA Castellano, DR Dance, CL Skinner, P Evans. Source of funding:The Royal Marsden

Computed tomography (CT) is probably the greatest single source of man-made medical radiation and the relationship between radiation dose to the patient and image quality must be optimised. This is particularly imperative for innovative screening procedures such as fast volume acquisition scans of smokers to detect lung cancer at an early stage. The first step in the process is the estimation of patient doses. We have developed a computer model to simulate the electron beam CT scanner, which is used for such scans. The radiation doses calculated agree with experimental measurements to within 10%. We have demonstrated that, for this scanner, patient doses are1mSv for a high resolution scanning technique, but as much as 7 mSv for a volume scan. Therefore great care must be exercised when choosing a scanning protocol for screening procedures.

Comparison of Monte Carlo calculations with experimental measurements at various locations within the AAPM head and body phantoms, using the 3 and 6 mm slice modes.


Towards a Simple Method for Evaluating Patient Doses in Computed Tomography
DR Dance, IA Castellano, CL Skinner; in collaboration with P Aviles, E Vano, Universidad Complutense de Madrid, Spain. Source of funding: EU, The Royal Marsden

We are developing methods of estimating radiation dose for computed tomography examinations using thermoluminescent dosimeters (TLD) placed on the patient's skin. This approach is more practical than the standard methodology, which uses large plastic phantoms and ionisation chambers. We have found that the skin dose depends strongly on the vertical position of the patient within the CT scanner gantry. We have developed a simple computational model which can accurately predict this vertical variation, and which can be used to correct dose measurements to those for a standard patient position. This work is directly applicable to CT fluoroscopy, a new technique for CT-guided biopsies that can potentially deliver high skin doses. We have demonstrated that patient skin doses can be considerably greater than those estimated using plastic phantoms, and thus the probability of causing skin erythema is greater than at first anticipated.

Unification of Physical and Clinical Requirements for Digital X-ray Imaging
DR Dance, RA Hunt, SH Evans, IA Castellano, CL Skinner; in collaboration with G Alm Carlsson, M Sandborg, G Ullman, Linkoping; groups from Braunschweig, Lausanne, Liverpool, Malmo, Magdeburg, Neuherberg Source of funding: EU, The Royal Marsden

This study is part of a large Fifth Framework EU funded collaboration to develop methods of quantifying and improving image quality in digital radiography of the breast and chest. Our contribution is a theoretical study of the influence of system design on image quality and radiation dose. We use Monte Carlo computational methods and a voxel phantom to simulate the radiographic examination. During the first year of this new project our main emphasis has been on the extension and validation of our existing computer model of the mammographic examination to simulate digital imaging systems. The resulting code can calculate the complete radiographic image as well as the necessary dosimetric quantities. It has been validated by comparison with measurements on our General Electric 2000D digital mammographic unit. Good agreement between measured and calculated pixel values and relative noise levels has been obtained.

Use of the Thomas Jefferson University Breast Phantom for Breast Dosimetry
DR Dance, RA Hunt; in collaboration with ADM Maidment and PR Bakic, Thomas Jefferson University; G Alm Carlsson, M Sandborg, Linköping. Source of funding: EU, The Royal Marsden

Our computer model of X-ray mammography has been extended to make use of realistic high resolution models of the breast, recently developed at Thomas Jefferson University. It allows for the first time dosimetry for individual breast tissues, and studies of the dependence of image properties on breast structure. The realistic breast phantoms have a voxel size of 200 or 400 micron and simulate in three dimensions adipose and fibro-glandular tissues, Cooper's ligaments, ducts and skin. The computer program calculates the dose to each tissue and image properties such as energy imparted and noise per pixel. In a preliminary study, doses to each tissue have been calculated for a phantom 50mm thick and a conventional Mo/MO spectrum. Doses (normalised to 100 for adipose tissue) are: fibroglandular tissue 92; ducts 87; skin 284; Cooper's ligaments 147. Variations in the scatter-to-primary ratio due to tissue inhomogeneity are 25%.



Calculated images of the Thomas Jefferson breast phantom. The upper image has been calculated using primary photons only. The lower image has reversed polarity and has been calculated with the attenuation in the ducts enhanced so that the ductal tree can be visualised.

Use of Scattered X-rays for the Detection and Characterisation of Breast Abnormalities
DR Dance, SH Evans; in collaboration with groups from CLRC Daresbury, Cranfield, Manchester, Nottingham. Source of funding: The Royal Marsden

We are part of a group led by the national synchrotron radiation laboratory at Daresbury studying the scattering and refraction of X-rays by breast tissue. The work is exploring the imaging potential of scattered x-rays for both the detection and characterisation of tumours. Images taken using the synchrotron radiation source in Trieste showed remarkable tumour contrast when a novel technique known as diffraction enhanced imaging was used. The practical potential of this and related techniques is continuing to be explored.

Development of an International Code of Practice for Patient Dosimetry in Diagnostic Radiology
DR Dance; in collaboration with G Alm Carlsson, Linköping; L De-Werd, Wisconsin; H-M Kramer, Braunschweig; K-H Ng, Malaysia, F Pernicka, Vienna Source of funding: International Atomic Energy Agency, The Royal Marsden

Medical X-ray examinations contribute greatly to the population dose from man-made radiation sources. A key stage in the process of controlling this dose is the standardisation of the procedures for instrument calibration and for dose measurement in the clinic. We are participating in a working group supported and co-ordinated by the International Atomic Energy Agency in Vienna, that is developing an international code of practice for instrument calibration and practical measurements in the clinic.

Influence of Operator Protocols on Effective Doses for Paediatric Computed Radiography
S Dhanse, IA Castellano, SH Evans. Source of funding: The Royal Marsden

The effect of operator protocols on effective dose for different aged infants, undergoing a chest x-ray using computed radiography has been investigated using a Monte Carlo program (PCXMC). Simulated doses received by new-born, 1year old and 5 year old infants were calculated. The effective dose was largely independent of the age of the infant for a given exposure protocol. In comparison to a well collimated x-ray field, the effective doses increased by 157%, 101% and 157% for the 0, 1, and 5 year old respectively when the collimators were open both laterally and longitudunally

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